Penicillin G sodium salt

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

苄青霉素钠是一种青霉素衍生物，通常以其钠盐或钾盐的形式用于治疗多种感染。

Benzylpenicillin sodium is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on gamma-aminobutyric acid mediated synaptic transmission.(In Vitro):The Ultraviolet-visible (UV-Vis) absorption spectrum of the Penicillin G sodium salt-TEM-1 system is markedly different to that of Penicillin G sodium salt and TEM-1 β-lactamase, indicating the formation of new complexes between Penicillin G sodium salt and TEM-1 β-lactamase. The UV-Vis absorption of TEM-1 β-lactamase increases and a slight red-shift occurs as the concentration of Penicillin G sodium salt increasing, indicating that the interaction between Penicillin G sodium salt and TEM-1 β-lactamase results in subtle conformational changes of TEM-1 β-lactamase.(In Vivo):In the logistic regression model, the probability of a positive swab in the control group is 1.6 times higher than that in the pigs treated with Penicillin G sodium salt (P<0.05). In the control group, the risk of a swab having 10 to 99 colonies per plate, compare to having zero per plate, is 2.3 times greater than that in the pigs treated with Penicillin G sodium salt (P=0.022).

The Ultraviolet-visible (UV-Vis) absorption spectrum of the Penicillin G sodium salt-TEM-1 system is markedly different to that of Penicillin G sodium salt and TEM-1 β-lactamase, indicating the formation of new complexes between Penicillin G sodium salt and TEM-1 β-lactamase. The UV-Vis absorption of TEM-1 β-lactamase increases and a slight red-shift occurs as the concentration of Penicillin G sodium salt increasing, indicating that the interaction between Penicillin G sodium salt and TEM-1 β-lactamase results in subtle conformational changes of TEM-1 β-lactamase.

In the logistic regression model, the probability of a positive swab in the control group is 1.6 times higher than that in the pigs treated with Penicillin G sodium salt (P<0.05). In the control group, the risk of a swab having 10 to 99 colonies per plate, compare to having zero per plate, is 2.3 times greater than that in the pigs treated with Penicillin G sodium salt (P=0.022).

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GPCR/G Protein

Antibacterial

PBPs| GABAR

Other Indications

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69-57-8

356.37

C16H17N2NaO4S

>98% (HPLC)

Water: 71 mg/mL (199.23 mM); DMSO: 71 mg/mL (199.23 mM)

CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[Na+]

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(-20℃)

With Ice Pack

≥ 2 years